Not Coordinated

Neuromodulators, not activity, control coordinated expression of ionic currents.

Electrical activity in identical neurons across individuals is often remarkably similar and stable over long periods. However, the ionic currents that determine the electrical activity of these neurons show wide animal-to-animal amplitude variability. This seemingly random variability of individual current amplitudes may obscure mechanisms that globally reduce variability and that contribute to...

Coordinated and Joint Ordering Policies for Two Commodity Inventory System

Polymerase and Exonuclease Activities in Herpes Simplex Virus Type 1 DNA Polymerase Are Not Highly Coordinated

The herpes polymerase-processivity factor complex consists of the catalytic UL30 subunit containing both polymerase and proofreading exonuclease activities and the UL42 subunit that acts as a processivity factor. Curiously, the highly active exonuclease has minimal impact on the accumulation of mismatches generated by the polymerase activity. We utilized a series of oligonucleotides of defined ...

Coordinated and Aerobic Exercise do not Improve Attention in Graduate Students

Acute coordinative exercise, represented by various sports skills requiring bilateral use of hands or feet, has been shown to improve attention in school age children in a classroom setting. The purpose of this investigation was to determine if acute aerobic and coordinative exercise improves attention in graduate students in the same setting. Twentyeight students (19 Women, 9 men; Age=24±1 yea...

Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment.

Transport of cellular and neuronal vesicles, organelles, and other particles along microtubules requires the molecular motor protein dynein (Mallik and Gross, 2004). Critical to dynein function is dynactin, a multiprotein complex commonly thought to be required for dynein attachment to membrane compartments (Karki and Holzbaur, 1999). Recent work also has found that mutations in dynactin can ca...